Transcranial ultrasound stimulation (TUS) is a non-invasive neuromodulation technique that employs focused ultrasound waves to modulate neuronal activity within the brain. TUS offers a promising avenue for therapeutic and research applications due to its spatial precision and ability to target deep neural structures.
The International Transcranial Ultrasonic Stimulation Safety and Standards (ITRUSST) consortium has formed a subcommittee, endorsed by the International Federation of Clinical Neurophysiology (IFCN), to develop recommendations for best practices in human TUS applications.
Reference:
K. R. Murphy, T. Nandi, B. Kop, T. Osada, M. Lueckel, W. Apoutou N’Djin, K. A. Caulfield, A. Fomenko, H. R. Siebner, Y. Ugawa, L. Verhagen, S. Bestmann, E. Martin, K. Butts Pauly, E. Fouragnan, T. Ole Bergmann, A practical guide to transcranial ultrasonic stimulation from the IFCN-endorsed ITRUSST consortium, in Clinical Neurophysiology, Volume 171, 2025, Pages 192-226. [View], [Download]