Setting a new standard for Transcranial Magnetic Stimulation
with collaborative robotics


Axilum Robotics TMS-Cobot is intended to control the positioning, the orientation and the contact of a compatible TMS coil under the supervision of an optical tracking system (no MRI) or a compatible neuronavigation system (MRI)


Axilum Robotics TMS-Cobot
Optical Tracking System
or compatible Neuronavigator
Treatment chair Axilum Robotics TMS-Cobot Compatible Coil and Stimulator

Why TMS-Cobot ?

There is an increasing awareness of Transcranial Magnetic Stimulation current suboptimal implementation when the coil is hold manually during sessions of more than 30 minutes, or attached to a passive holder, forcing the patient to stay perfectly still.
The issue is even more important when a neuronavigation is used for MRI guidance

Evaluating the impact of suboptimal coil positionning

Coil rotation impact
Coil positioning techniques impact
Toschi et al. (1) have demonstrated the significant clinical impact of small rotations in coil position (i.e. 7°), with variation of 25% or more of the stimulus intensity and MEP drop by 60% Richter et al. (2) have shown that with a passive holder, the induced electric field can decrease by 30% over a 30 mn period (coil holder and avoiding head motion) and still 20% when using a head rest, while robotic motion compensation results in clinically acceptable positioning throughout treatment


Moreover, with an increasing number of patients to treat, there is an increasing need to deliver the operator from a demanding and time-consuming task and to reallocate part of his time to more value-added tasks.

Finally, to avoid any head motion during a 30 mn period, even with a head rest, is a real constraint for the patient

Our objective, with TMS-Cobot is to provide an affordable robotic solution, with head motion compensation, to improve the precision of the procedure while delivering the operator from a demanding and repetitive task and reducing the constraints for the patient.
It is important for the user to maximize the chance to deliver the stimulation dose at the right location and TMS-Cobot make this possible.

Key features

  • Collaborative robotics « cobot » technology (safety)
    Such technology provides intrinsic safety features through a collision detection mechanism at each joint level, allowing close collaboration with human beings.  Movements of the robotic arm can be either automated or manually directed by the user having activated a so-called free-drive mode
  • Keeps the position and the orientation of the TMS coil during the session (optical tracking of markers on the head)
  • Compensates for potential head motion during the TMS session
  • Ensures permanent contact between coil and head (integrated pressure sensor)
  • Compatible with any chair
  • Lightweight and highly mobile : Can easily be moved on its wheels
  • Ergonomy : When piloted by a compatible neuronavigation system, the operator controls TMS-Cobot from the graphical user interface of the neuronavigator
    When piloted by Axilum Robotics optical Tracking System, the operator controls TMS-Cobot from a control panel placed on the cart

Key advantages

  • Improves accuracy and repeatability
    Accuracy of the robotic arm is below 2 mm
  • Delivers the operator from a repetitive, painful and and time consuming task
    Once the session launched, minimal attention of the operator is requested to ensure appropriate position, orientation and contact of the coil on the head


  • TMS-Cobot is compatible with coils from Deymed, Magstim, MagVenture, Mag&More, Neurosoft. List of compatible coils on request
  • TMS-Cobot can be piloted either by Axilum Robotics optical Tracking System (without MRI) or compatible neuro-navigation system from Localite, Rogue Research/Brainsight, Syneika

Dimensions and Weight

TMS-Cobot fits to any space and enters into most elevators thanks to its practical dimensions and light weight.

  • Height with arm : (H) 1770 mm
  • Base dimensions : (L x W)1111 x 650 mm
  • Weight : 143 kg

Regulatory information

  • CE Mark (EU) :

TMS-Cobot is a class IIa medical device, intended to automate and improve the accuracy and the repeatability of the positioning of a Transcranial Magnetic Stimulation (TMS) coil, in the clinical situations where compatible devices are intended to be used, with the exception of peripheral nerve stimulation. It bears the CE marking 1639 whose conformity assessment has been established by the notified body SGS. Read the user manual before any use. These medical devices are not reimbursed by French health insurance.

  • FDA 510(k) clearance (USA) :

Axilum Robotics TMS-Cobot® TS MV is indicated for the spatial positioning and orientation of the treatment coil of the MagVenture TMS Therapy system (FDA clearance K182768 Class II).


Comparison between TMS-Cobot and TMS-Robot





Compatible stimulator and coil
 Piloted by compatible neuronavigation system

(option 1)
 Piloted by tracking system (No MRI)

(option 2)
 Patient seat
 Included, with electric adjustment Compatible with any treatment chair
 Coil guidance
Robotized  Robotized
+ manual pre-positionning
 Working space


½ Hemi-spherical
 Head motion tracking
 Coil contact sensor
(by design)
(collaborative robot)
 1 mm (ref space of NN)  < 2 mm (arm accuracy)
 0,1 mm < 2 mm
Regulatory status
For medical or scientific investigation purposes only
Non FDA cleared
CE mark – class IIa
FDA cleared


(1) Toschi N. et al. Transcranial magnetic stimulation in heterogeneous brain tissue: clinical impact on focality, reproducibility and true sham stimulation. J Psychiatr Res. 2009 Jan;43(3):255-64.
(2) Richter L et al. Stimulus intensity for hand held and robotic transcranial magnetic stimulation. Brain Stimul. 2013 May;6(3):315-21. doi: 10.1016/j.brs.2012.06.002. Epub 2012 Jun 21.