Once the stimulation targets and coil self-rotation have been defined in the neuronavigation system, Axilum Robotics TMS-Robot positions the coil tangentially at these targets, ensures contact between coil and head, and compensates for any head movement during the session, keeping the coil position and orientation with respect to the brain. TMS-Robot will allow to considerably improve the spatial resolution of the TMS stimulation in healthy subjects and in patients with neurological or psychiatric disorders.

In a study published in 2013 [2] comparing navigated, robotic coil positioning with TMS-Robot versus manual coil positioning for motor cortex mapping using healthy volunteers, absolute and test-retest reliability were significantly improved by robotic assistance (p < 0.01 for all tests) by a factor of 2 (~3 mm vs. ~6 mm). Of special interest was the number of stimulations that were below 5 mm from the target. Whereas this rate was as low as 50% under manual conditions, it increased to 90% with the robot-controlled coil placement.

Histogram of the accuracy with pre-contractionsRepeatability between the two consecutive sessions

Absolute reliability (left) and test-retest reliability (right) comparing manual versus robotic coil positioning [2].

For more information, please check out the publication:

R. Ginhoux, P. Renaud, L. Zorn, L. Goffin, B. Bayle, J. Foucher, J.P. Armspach and M. de Mathelin, A Custom Robot for Transcranial Magnetic Stimulation: First Assessment on Healthy Subjects, Proceedings of the 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’13), Osaka, Japan, July 3-7, 2013. [Download].